IntroductionThe introduction of innovative therapies, resulting from revisiting cancer as a disease of the immune system, has changed the scenario of complications.These new classes of drugs, such as targeted therapies and immune checkpoint inhibitors, assure substantial advantages in cancer therapy, despite some side effects affecting various orga
Objective: Obtaining hhigh-yield pprotease-pproducing bacterial resources through fermentation of advantageous protease-producing strains derived from Shiping stinky tofu.Methods: Single-factor and response surface experiments were used to optimize the culture medium and fermentation conditions.Using casein as the substrate, the effects of temperat
After being declared as a pandemic on March 11, 2020 by the World Health Organization, COVID-19 has affected 497 million people worldwide as of 9 April 2022.COVID-19 is a disease with a plethora of clinical manifestations, which extends to those beyond pulmonary signs and symptoms.Studies that report on the clinical presentation of COVID-19 rarely
Marcelo Vivolo Aun,1,2 Rafael Bonamichi-Santos,1,2 Fernanda Magalhães Arantes-Costa,2 Jorge Kalil,1 Pedro Giavina-Bianchi1 1Clinical Immunology and Allergy Division, Department of Internal Medicine, University of São Paulo School of Medicine, São Paulo, Brazil, 2Laboratory of Experimental Therapeutics (LIM20), Department of Int
One of the most powerful political concepts in Europe, including Latvia, is the welfare state.Whether or not the Latvian language environment reveals hopes and expectations regarding the notion may be determined through a close study of the parliamentary discourse of the past five years, as well as the language user opinions regarding state.The goa